Anthelmintic Activity of Salvadora Persica Root Extract against Pheretima Posthuma

نویسنده

  • S. Abdul Majeed
چکیده

Helminthes infections are the most common health problems in India, in developing countries they pose a large treat to public. These infections can affect most population in endemic areas with major economic and social consequences. The miswak is a natural toothbrush made from the twigs of the Salvadora persica (Salvadoraceae). Miswak prevents tooth decay, eliminating toothaches and halt further increase in decay. The present study was undertaken to evaluate antihelmintic activity of aqueous and alcoholic root extract of S. persica against Indian earthworms Pheretima posthuma. Various concentrations (10, 20, 40 and 80 mg/ml) of aqueous and alcoholic root extract of S. persica were tested, which involved determination of time of paralysis and time of death of the worms. It was compared with Piperazine citrate (10, 20, 40 and 80 mg/ml) as standard reference and normal saline as control. The study indicated the potential usefulness of aqueous and alcoholic extract of S. persica against earthworm. INTRODUCTION: Helminthiasis or worm infestation is one of the most prevalent disease and one of the most serious public health problems in the world. Hundreds of millions if not billions of human infections by helminthes exist worldwide and increased world travel and immigration from the developing countries . Chemical control of helminthes coupled with improved management has been the important worm control strategy throughout the world. However, increasing problems of development of resistance in helminthes 2, 3 against anthelmintics have led to the proposal of screening medicinal plants for their antihelmintic activity. Medicinal plants are of great importance to the health of individuals and communities in general. The medicinal value of plants lies in some chemical substances that produce a definite physiological action on the human body. The most important of these bioactive constituents of plants are alkaloids, tannins, flavonoids and phenolic compounds. Many of the indigenous medicinal plants are used as spices and food plants. They also sometimes added to foods meant for pregnant women and nursing mothers for medicinal purposes 4, 5, . In addition, the use of herbal medicine for the treatment of diseases and infections is as old as mankind. The World Health Organization supports the use traditional medicine provided they are proven to be efficacious and safe . In developing countries, a huge number of people lives in extreme poverty and some are suffering and dying for want of safe water and medicine, they have no alternative for primary health care . Therefore, the need to use medicinal plants as alternatives to orthodox medicines in the provision of primary health care cannot be overemphasized.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

In-Vitro Anthelmintic Activity of Luffa cylindrica Leaves in Indian Adult Earthworm

Different extracts of L. cylindrica were taken for anthelmintic activity against Indian earthworm Pheretima posthuma. Two concentrations (50 and 100 mg/ml) of various extracts were tested and results were expressed in terms of time for paralysis and time for death of worms. Albendazole (20 mg/ml) was used as reference standard and carboxy methyl cellulose (0.5%) as a control group. Dose depende...

متن کامل

Anthelmintic activity of root bark of Carissa carandas

The anthelmintic activity of the Imethanolic extract of the root bark of Carissa carandas was evaluated on adult Indian earthworm (Pheretima posthuma) using albendazole as a reference standard. The extract caused paralysis followed by the death of worm at the tested dose level. The extract at the highest tested concentration has anthelmintic activity comparable with that of standard drug albend...

متن کامل

In–vitro Anthelmintic Activity of Pet – Ether Extract of Portulaca Oleracea (linn.) against Pheritima Posthuma

Present study was carried out to investigate the anthelmintic potential of petroleum-ether extract of Portulaca oleracea against Pheretima posthuma as a species of earthworm. Various concentrations (25‐100 mg/ml) of petroleum-ether extract were evaluated for anthelmintic activity by recording the time required for paralysis and death of worms. Albendazole was used as standard. Result indicates ...

متن کامل

Anthelmintic activity of Argemone mexicana leaves extract against Pheretima prosthuma and Ascardia galli

Alcohol and aqueous extracts from the leaves of Argemone mexicana were investigated for their anthelmintic activity against Pheretima posthuma and Ascardia galli. Five concentrations (6.25, 12.5, 25, 50 and 100 mg/ml) of each extracts were studied in activity, which involved the determination of time of paralysis and time of death of the worms. Both the extracts exhibited significant anthelmint...

متن کامل

IN VITRO ANTHELMINTIC ACTIVITY OF AQUEOUS AND METHANOLIC LEAF EXTRACT OF Tephrosia purpurea LINN

Tephrosia purpurea is a copiously branched herbaceous perennial plant distributed throughout the tropics which is used in the treatment of bronchitis, diuretic, pimples, tonic, laxative, cough, and tumour. The present study is an attempt to explore the anthelmintic activity of aqueous and methanolic extract of leaves of plant Tephrosia purpurea . The various concentrations of aqueous and methan...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2011